Job Detail

Job Position - Department

Medical Officer - EndTB Clinical Trial - GHD


At least 6-months experience in managing patients with MDR-TB in a primary care context


MBBS (or equivalent) degree with at least 2 years of clinical experience in an OPD setting. • Current registration with the Pakistan Medical & Dental Council (PMDC)

Last Date

1/26/2020 12:00:00 AM

Job Description

The incumbent will provide quality medical care to eligible rifampicin-resistant TB patients of a phase III randomized controlled, and to conduct trial procedures in accordance with the protocol and Good Clinical Practice (GCP).

  • Undergo training in the protocol, trial procedures, and GCP.
  • Engage with clinic staff, and assist endTB trial staff and counsellors to identify and recruit potentially eligible rifampicin-resistant TB patients for the trial.
  • Together with a research nurse, perform screening procedures for potential participants to assess eligibility for the trial.
  • Together with a research nurse, perform trial follow up visits and associated procedures in accordance with the protocol and GCP.
  • Prescribe study drugs, ancillary drugs, and antiretroviral agents (if needed) to trial participants.
  • Perform medical assessments at every trial visit (and at unscheduled visits) to monitor clinical progress and to assess for adverse events.
  • Perform medical assessments and follow up visits of trial participants in hospital when necessary.
  • Assist research nurses with trial procedures, including phlebotomy, ECGs, toxicity screening.
  • Complete Case Report Forms and other trial documents.
  • Discuss clinical problems with the site Principal Investigator, and prepare reports for the trial Clinical Advisory Committee (CAC) where appropriate.
  • Engage with clinic staff and other members of the team to identify medical problems or difficulty with adherence to study drugs.
  • Liaise with clinic staff, including doctors, nurses, and counsellors, to share and discuss clinical progress of trial participants.
  • Maintain regular contact with clinic doctors regarding the recruitment and management of trial participants. This includes writing and responding to referral letters where required.
  • Travel to trial clinic sites in Karachi.
  • Compile reports on serious adverse events, and communicate these to the trial pharmacovigilance unit and local regulatory authorities (together with the Trial Coordinator and site Principal Investigator)
  • Assist with quality control and data entry and management.
  • Attend regular meetings with the endTB trial team.